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KMID : 0811820100140020218
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Journal of Korean Society of Pediatric Nephrology
2010 Volume.14 No. 2 p.218 ~ p.222
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A Case of Nephrotic Syndrome with Swine-origin H1N1 Influenza Virus
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Kim Sae-Yoon
Kim Myung-Uk
Lee Sang-Su
Park Yong-Hoon
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Abstract
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Nephrotic syndrome is a clinical syndrome characterized by heavy proteinuria, hypoalbuminemia, edema and hyperlipidemia. Causes of idiopathic nephrotic syndrome include minimal change nephrotic syndrome (MCNS), focal segmental glomerulosclerosis (FSGS) and mesangial proliferation. Other causes of nephrotic syndrome are rare genetic disorders and secondary diseases associated with drugs, infections, or neoplasia. Since February 2009, a swine-origin H1N1 influenza virus (S-OIV) from Mexico has been spread among humans in unexpected rapidity. S-OIV is markedly different from seasonal influenza, in that many of those affected are previously healthy young people. While pulmonary complications of S-OIV infection have been frequently documented, renal complications have not been as widely recognized. We report a case of 4 year-old boy who had developed nephrotic syndrome after S-OIV infection with good response after steroid treatment.
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KEYWORD
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H1N1 influenza, Nephrotic syndrome, Oseltamivir
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